Hi,
Yes this can cause problem .
Here is KB article which explain the check condition.
vmkernel: 76:23:45:36.239 cpu11:22687)NMP: nmp_CompleteCommandForPath: Command 0x28 (0x41000b10f000) to NMP device "naa.600601601f70190016361881f3b4de11" failed on physical path "vmhba3:C0:T2:L10" H:0x0 D:0x2 P:0x0 Valid sense data: 0x2 0x4 0x3.
This status is returned when a command fails for a specific reason. When a CHECK CONDITION is received, the ESX storage stack will send out a SCSI command 0x3 (REQUEST SENSE) in order to get the SCSI sense data (Sense Key, Additional Sense Code, ASC Qualifier, and other bits). The sense data is listed after "Valid sense data" in the order of Sense Key, Additional Sense Code, and ASC Qualifier. When decoding Additional Sense Code/ASC Qualifier bits, they must be read together. Here is a breakdown of the above message:
Host Status = 0x0 = OK
Device Status = 0x2 = Check Condition
Regards
Mohammed